Thrombin Preconditioning Enhances Therapeutic Efficacy of Human Wharton’s Jelly–Derived Mesenchymal Stem Cells in Severe Neonatal Hypoxic Ischemic Encephalopathy

We investigated whether thrombin preconditioning of human Wharton’s jelly–derived mesenchymal stem cells (MSCs) improves paracrine potency and thus the therapeutic efficacy of naïve MSCs against severe hypoxic ischemic encephalopathy (HIE). Thrombin preconditioning significantly enhances the neuropr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Young Eun, Sung, Se In, Chang, Yun Sil, Ahn, So Yoon, Sung, Dong Kyung, Park, Won Soon
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566845/
https://ncbi.nlm.nih.gov/pubmed/31137455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102477
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