Mitochondrial-Derived Vesicles as Candidate Biomarkers in Parkinson’s Disease: Rationale, Design and Methods of the EXosomes in PArkiNson Disease (EXPAND) Study

The progressive loss of dopaminergic neurons in the nigro-striatal system is a major trait of Parkinson’s disease (PD), manifesting clinically as motor and non-motor symptoms. Mitochondrial dysfunction and oxidative stress are alleged pathogenic mechanisms underlying aggregation of misfolded α-synuc...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Picca, Anna, Guerra, Flora, Calvani, Riccardo, Bucci, Cecilia, Lo Monaco, Maria Rita, Bentivoglio, Anna Rita, Landi, Francesco, Bernabei, Roberto, Marzetti, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
Assuntos:
Perspective
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566801/
https://ncbi.nlm.nih.gov/pubmed/31091653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102373
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