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Direct Enantiomeric Resolution of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives by HPLC

1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic mixture, the chiral center at C-4 can lead to even opposite pharmacological acti...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Sun, Jiayi, Gözde Gündüz, Miyase, Zhang, Junyuan, Yu, Jia, Guo, Xingjie
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566779/
https://ncbi.nlm.nih.gov/pubmed/31121823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102513
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