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ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer
The extracellular signal-related kinases (ERKs) act as pleiotropic molecules in tumors, where they activate pro-survival pathways leading to cell proliferation and migration, as well as modulate apoptosis, differentiation, and senescence. Given its central role as sensor of extracellular signals, ER...
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| Veröffentlicht in: | Int J Mol Sci |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MDPI
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6566596/ https://ncbi.nlm.nih.gov/pubmed/31117237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20102505 |
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