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Small Interference RNA Targeting Connexin-43 Improves Motor Function and Limits Astrogliosis After Juvenile Traumatic Brain Injury

Juvenile traumatic brain injury (jTBI) is the leading cause of death and disability for children and adolescents worldwide, but there are no pharmacological treatments available. Aquaporin 4 (AQP4), an astrocytic perivascular protein, is increased after jTBI, and inhibition of its expression with sm...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:ASN Neuro
Hauptverfasser: Ichkova, Aleksandra, Fukuda, Andrew M., Nishiyama, Nina, Paris, Germaine, Obenaus, Andre, Badaut, Jerome
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566476/
https://ncbi.nlm.nih.gov/pubmed/31194577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759091419847090
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