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Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates

The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates forming acyclic all-carbon quaternary stereocenters is reported. Excellent yields up to 99% and enantioselectivities up to 98% ee are obtained through the use...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Alexy, Eric J., Fulton, Tyler J., Zhang, Haiming, Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566452/
https://ncbi.nlm.nih.gov/pubmed/31360407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01726g
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