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Mitochondrial dysfunction in neurodegenerative diseases and the potential countermeasure

Mitochondria not only supply the energy for cell function, but also take part in cell signaling. This review describes the dysfunctions of mitochondria in aging and neurodegenerative diseases, and the signaling pathways leading to mitochondrial biogenesis (including PGC‐1 family proteins, SIRT1, AMP...

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Publicat a:CNS Neurosci Ther
Autors principals: Wang, Yan, Xu, Erin, Musich, Phillip R., Lin, Fang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6566063/
https://ncbi.nlm.nih.gov/pubmed/30889315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13116
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