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The FOXO3-FOXM1 axis: A key cancer drug target and a modulator of cancer drug resistance
The FOXO3 and FOXM1 forkhead box transcription factors, functioning downstream of the essential PI3K-Akt, Ras-ERK and JNK/p38MAPK signalling cascades, are crucial for cell proliferation, differentiation, cell survival, senescence, DNA damage repair and cell cycle control. The development of resistan...
Gorde:
| Argitaratua izan da: | Semin Cancer Biol |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Academic Press
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6565931/ https://ncbi.nlm.nih.gov/pubmed/29180117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.11.018 |
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