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Pitx2a Expression Alters Actin-Myosin Cytoskeleton and Migration of HeLa Cells through Rho GTPase Signaling

We ectopically expressed the transcription factor Pitx2a, one of the Pitx2 isoforms, in HeLa cells by using a tetracycline-inducible expression system and examined whether Pitx2a was capable of modulating Rho GTPase signaling and altering the cell's cytoskeleton. Ectopic expression of Pitx2a induced...

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Publicat a:Mol Biol Cell
Autors principals: Wei, Qize, Adelstein, Robert S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 2002
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC65659/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854422/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.01-07-0358
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