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Emergence of plasmid stability under non-selective conditions maintains antibiotic resistance

Plasmid acquisition is an important mechanism of rapid adaptation and niche expansion in prokaryotes. Positive selection for plasmid-coded functions is a major driver of plasmid evolution, while plasmids that do not confer a selective advantage are considered costly and expected to go extinct. Yet,...

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Vydáno v:Nat Commun
Hlavní autoři: Wein, Tanita, Hülter, Nils F., Mizrahi, Itzhak, Dagan, Tal
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565834/
https://ncbi.nlm.nih.gov/pubmed/31197163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10600-7
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