The zinc transporter Zip14 (SLC39a14) affects Beta-cell Function: Proteomics, Gene expression, and Insulin secretion studies in INS-1E cells

Insulin secretion from pancreatic beta-cells is dependent on zinc ions as essential components of insulin crystals, zinc transporters are thus involved in the insulin secretory process. Zip14 (SLC39a14) is a zinc importing protein that has an important role in glucose homeostasis. Zip14 knockout mic...

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Pubblicato in:Sci Rep
Autori principali: Maxel, Trine, Smidt, Kamille, Petersen, Charlotte C., Honoré, Bent, Christensen, Anne K., Jeppesen, Per B., Brock, Birgitte, Rungby, Jørgen, Palmfeldt, Johan, Larsen, Agnete
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565745/
https://ncbi.nlm.nih.gov/pubmed/31197210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44954-1
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