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Autoradiographic localization of (125I-Tyr4)bombesin-binding sites in rat brain

The binding of (125I-Tyr4)bombesin to rat brain slices was investigated. Radiolabeled (Tyr4)bombesin bound with high affinity (Kd = 4 nM) to a single class of sites (Bmax = 130 fmol/mg of protein); the ratio of specific to nonspecific binding was 6/1. Also, pharmacology studies indicated that the C-...

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Publié dans:J Neurosci
Auteurs principaux: Zarbin, MA, Kuhar, MJ, O'Donohue, TL, Wolf, SS, Moody, TW
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1985
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565205/
https://ncbi.nlm.nih.gov/pubmed/3973677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.05-02-00429.1985
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