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Kinetics and autoradiography of high affinity uptake of serotonin by primary astrocyte cultures

Primary astrocyte cultures prepared from the cerebral cortices of neonatal rats showed significant accumulation of serotonin (5- hydroxytryptamine; [3H]-5-HT). At concentrations in the range of 0.01 to 0.7 microM [3H]-5-HT, this uptake was 50 to 85% Na+ dependent and gave a Km of 0.40 +/- 0.11 micro...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Katz, DM, Kimelberg, HK
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565125/
https://ncbi.nlm.nih.gov/pubmed/4020424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.05-07-01901.1985
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