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The effects of a myasthenic serum on the acetylcholine receptors of C2 myotubes. I. Immunological distinction between the two toxin-binding sites of the receptor

We have examined the effect of a serum from a patient with myasthenia gravis on the binding of alpha-bungarotoxin (alpha-BuTx) to the acetylcholine receptors (AChRs) of a mouse muscle cell line, C2. After a 2-hr incubation, antibodies in the serum reduced toxin binding to C2 myotubes to a maximal ex...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gu, Y, Silberstein, L, Hall, ZW
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565115/
https://ncbi.nlm.nih.gov/pubmed/4020425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.05-07-01909.1985
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