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Autoradiographic localization of thyrotropin-releasing hormone receptors in the rat central nervous system

We employed quantitative autoradiography to examine the distribution of thyrotropin-releasing hormone (TRH) receptors in the rat CNS. The binding of [3H]3-methyl-histidine-TRH [( 3H]MeTRH) to TRH receptors in frozen rat brain sections was saturable, of a high affinity (Kd = 5 nM), and specific for T...

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發表在:J Neurosci
Main Authors: Manaker, S, Winokur, A, Rostene, WH, Rainbow, TC
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 1985
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6565072/
https://ncbi.nlm.nih.gov/pubmed/2981297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.05-01-00167.1985
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