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Nerve growth factor-mediated induction of choline acetyltransferase in PC12 cells: evaluation of the site of action of nerve growth factor and the involvement of lysosomal degradation products of nerve growth factor

In previous experiments it has been demonstrated that nerve growth factor (NGF), subsequent to its binding to specific membrane receptors, is internalized. Ultrastructurally, this internalized NGF is localized in membrane-confined compartments which ultimately fuse with lysosomes. The present experi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Heumann, R, Schwab, M, Merkl, R, Thoenen, H
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564859/
https://ncbi.nlm.nih.gov/pubmed/6502222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.04-12-03039.1984
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