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Somatostatin pretreatment desensitizes somatostatin receptors linked to adenylate cyclase and facilitates the stimulation of cyclic adenosine 3':5'-monophosphate accumulation in anterior pituitary tumor cells
Somatostatin-14 (SRIF) inhibits both hormone- and forskolin-stimulated cyclic adenosine 3′:5′-monophosphate (cyclic AMP) formation in tumor cells of the mouse anterior pituitary (AtT-20/D16–16). However, long- term pretreatment of cells with SRIF modifies the responsiveness of this system in two way...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
1984
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6564817/ https://ncbi.nlm.nih.gov/pubmed/6142935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.04-03-00812.1984 |
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