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Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii

Toxoplasma gondii is a prevalent protozoan parasite that can infect any nucleated cell but cannot replicate outside of its host cell. Toxoplasma is auxotrophic for several nutrients including arginine, tryptophan, and purines, which it must acquire from its host cell. The demands of parasite replica...

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Vydáno v:PLoS Pathog
Hlavní autoři: Augusto, Leonardo, Amin, Parth H., Wek, Ronald C., Sullivan, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564765/
https://ncbi.nlm.nih.gov/pubmed/31194856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007746
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