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Characterization of the peptide and sensory neurotoxic effects of capsaicin in the guinea pig

The effects of capsaicin, the major pungent ingredient of hot peppers, were assessed on sensory neuron neuropeptide levels and on sensory function in the adult guinea pig. Systemic doses of capsaicin as low as 2.5 mg/kg depleted substance P (SP) in dorsal roots plus ganglia (DRG) whereas a 10-mg/kg...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Buck, SH, Walsh, JH, Davis, TP, Brown, MR, Yamamura, HI, Burks, TF
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564576/
https://ncbi.nlm.nih.gov/pubmed/6194277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.03-10-02064.1983
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