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Differential regulation of the mu-, delta-, and kappa-opiate receptor subtypes by guanyl nucleotides and metal ions

The effects of Na+, guanyl-5′-yl imidodiphosphate (Gpp(MH)p), and Mn2+ on the binding of dihydromorphine, ethylketocyclazocine, D-Ala2, D-Leu5- enkephalin, and diprenorphine to the opiate receptor were investigated. Three distinct binding sites, mu, delta, and kappa sites, were identified with the u...

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Publicado en:J Neurosci
Autores principales: Pfeiffer, A, Sadee, W, Herz, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 1982
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564396/
https://ncbi.nlm.nih.gov/pubmed/6284888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.02-07-00912.1982
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