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Evolution of interface binding strengths in simplified model of protein quaternary structure

The self-assembly of proteins into protein quaternary structures is of fundamental importance to many biological processes, and protein misassembly is responsible for a wide range of proteopathic diseases. In recent years, abstract lattice models of protein self-assembly have been used to simulate t...

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Pubblicato in:PLoS Comput Biol
Autori principali: Leonard, Alexander S., Ahnert, Sebastian E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6564041/
https://ncbi.nlm.nih.gov/pubmed/31158218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006886
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