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Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization

Signal transduction activated by Wingless/Wnt ligands directs cell proliferation and fate specification in metazoans, and its overactivation underlies the development of the vast majority of colorectal cancers. In the conventional model, the secretion and movement of Wingless to cells distant from i...

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Pubblicato in:PLoS Genet
Autori principali: Tian, Ai, Duwadi, Deepesh, Benchabane, Hassina, Ahmed, Yashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563961/
https://ncbi.nlm.nih.gov/pubmed/31194729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008111
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