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Hypermethylation: Causes and Consequences in Skeletal Muscle Myopathy

A detrimental consequence of hypermethylation is hyperhomocysteinemia (HHcy), that causes oxidative stress, inflammation, and matrix degradation, which leads to multi-pathology in different organs. Although, it is well known that hypermethylation leads to overall gene silencing and hypomethylation l...

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Detalhes bibliográficos
Publicado no:J Cell Biochem
Main Authors: Majumder, Avisek, Behera, Jyotirmaya, Jeremic, Nevena, Tyagi, Suresh C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563903/
https://ncbi.nlm.nih.gov/pubmed/27982479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25841
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