Genomic amplification of chromosome 7 in the Doxorubicin resistant K562 cell line

Acquisition of multi-drug resistance (MDR) is a major hindrance towards the successful treatment of cancers. Over expression of a range of ATP-dependent efflux pumps, particularly ABCB1 is a widely reported mechanism of cancer cell MDR. Approximately 30% acute myeloid leukemia (AML) patients demonst...

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Dettagli Bibliografici
Pubblicato in:Bioinformation
Autori principali: Ibrahim, Sara.M, Karim, Sajjad, Abusamra, Heba, Pushparaj, Peter N, Khan, Jalaluddin A, Abuzenadah, Adel M, Gari, Mamdooh A, Bakhashab, Sherin, Ahmed, Farid, Al-Qahtani, Mohammed H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biomedical Informatics 2018
Soggetti:
Hypothesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563671/
https://ncbi.nlm.nih.gov/pubmed/31223218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630014587
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