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On the Origin of Testicular Germ Cell Tumors: From Gonocytes to Testicular Cancer

Human primordial germ cells (PGCs) have been described in the yolk sac wall around the beginning of the third week. From week 4 to 5, they migrate under control of SCF/c-KIT signaling pathway to the genital ridge, where they become gonocytes. PGCs and gonocytes express classic pluripotency markers,...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Baroni, Tiziano, Arato, Iva, Mancuso, Francesca, Calafiore, Riccardo, Luca, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563414/
https://ncbi.nlm.nih.gov/pubmed/31244770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00343
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