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Targeted Editing of the pp38 Gene in Marek’s Disease Virus-Transformed Cell Lines Using CRISPR/Cas9 System

Marek’s disease virus (MDV), a lymphotropic α-herpesvirus associated with T-cell lymphomas in chickens, is an excellent model for herpesvirus biology and virus-induced oncogenesis. Marek’s disease (MD) is also one of the cancers against which a vaccine was first used. In the lymphomas and lymphoblas...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Zhang, Yaoyao, Luo, Jun, Tang, Na, Teng, Man, Reddy, Vishwanatha R.A.P., Moffat, Katy, Shen, Zhiqiang, Nair, Venugopal, Yao, Yongxiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563304/
https://ncbi.nlm.nih.gov/pubmed/31027375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11050391
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