Fusaoctaxin A, an Example of a Two-Step Mechanism for Non-Ribosomal Peptide Assembly and Maturation in Fungi

Fungal non-ribosomal peptide synthetase (NRPS) clusters are spread across the chromosomes, where several modifying enzyme-encoding genes typically flank one NRPS. However, a recent study showed that the octapeptide fusaoctaxin A is tandemly synthesized by two NRPSs in Fusarium graminearum. Here, we...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Westphal, Klaus Ringsborg, Nielsen, Katrine Amalie Hamborg, Wollenberg, Rasmus Dam, Møllehøj, Mathias Bonde, Bachleitner, Simone, Studt, Lena, Lysøe, Erik, Giese, Henriette, Wimmer, Reinhard, Sørensen, Jens Laurids, Sondergaard, Teis Esben
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563249/
https://ncbi.nlm.nih.gov/pubmed/31100892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11050277
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