Novel Thienopyrimidine Derivative, RP-010, Induces β-Catenin Fragmentation and Is Efficacious against Prostate Cancer Cells

Thienopyrimidines containing a thiophene ring fused to pyrimidine are reported to have a wide-spectrum of anticancer efficacy in vitro. Here, we report for the first time that thieno[3,2-d]pyrimidine-based compounds, also known as the RP series, have efficacy in prostate cancer cells. The compound R...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Amawi, Haneen, Hussein, Noor, Boddu, Sai H. S., Karthikeyan, Chandrabose, Williams, Frederick E., Ashby, Charles R., Raman, Dayanidhi, Trivedi, Piyush, Tiwari, Amit K.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6563099/
https://ncbi.nlm.nih.gov/pubmed/31126091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050711
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