NDRG2 Sensitizes Myeloid Leukemia to Arsenic Trioxide via GSK3β–NDRG2–PP2A Complex Formation

N-Myc downstream-regulated gene 2 (NDRG2) was characterized as a tumor suppressor, inducing anti-metastatic and anti-proliferative effects in several tumor cells. However, NDRG2 functions on anticancer drug sensitivity, and its molecular mechanisms are yet to be fully investigated. In this study, we...

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Pubblicato in:Cells
Autori principali: Park, Soojong, Han, Hyun-Tak, Oh, Sang-Seok, Kim, Dong Hyeok, Jeong, Jin-Woo, Lee, Ki Won, Kim, Minju, Lim, Jong Seok, Cho, Yong Yeon, Hwangbo, Cheol, Yoo, Jiyun, Kim, Kwang Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562968/
https://ncbi.nlm.nih.gov/pubmed/31121982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050495
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