Molecular Pathogenesis of Gene Regulation by the miR-150 Duplex: miR-150-3p Regulates TNS4 in Lung Adenocarcinoma

Based on our miRNA expression signatures, we focused on miR-150-5p (the guide strand) and miR-150-3p (the passenger strand) to investigate their functional significance in lung adenocarcinoma (LUAD). Downregulation of miR-150 duplex was confirmed in LUAD clinical specimens. In vitro assays revealed...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Misono, Shunsuke, Seki, Naohiko, Mizuno, Keiko, Yamada, Yasutaka, Uchida, Akifumi, Sanada, Hiroki, Moriya, Shogo, Kikkawa, Naoko, Kumamoto, Tomohiro, Suetsugu, Takayuki, Inoue, Hiromasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562801/
https://ncbi.nlm.nih.gov/pubmed/31052206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11050601
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