High sensitivity methods to quantify chloroquine and its metabolite in human blood samples using LC–MS/MS

AIM: Chloroquine is an antimalarial drug used in the treatment of Plasmodium vivax malaria. Three methods to quantify chloroquine and its metabolite in blood matrices were developed and validated. METHODOLOGY & RESULTS: Different high-throughput extraction techniques were used to recover the dru...

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Vydáno v:Bioanalysis
Hlavní autoři: Kaewkhao, Karnrawee, Chotivanich, Kesinee, Winterberg, Markus, Day, Nicholas PJ, Tarning, Joel, Blessborn, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: Future Science Ltd 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562699/
https://ncbi.nlm.nih.gov/pubmed/30873854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2018-0202
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