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White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation

Obesity is associated with white adipose tissue (WAT) hypoxia and inflammation. We aimed to test whether mild environmental oxygen restriction (OxR, 13% O(2)), imposing tissue hypoxia, triggers WAT inflammation in obese mice. Thirteen weeks diet-induced obese male adult C57BL/6JOlaHsd mice housed at...

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Publicado en:Genes (Basel)
Main Authors: Hoevenaars, Femke P. M., Keijer, Jaap, van der Stelt, Inge, Duivenvoorde, Loes P. M., Herreman, Laure, van Nes, Robin, Friedecký, David, Hegeman, Maria A., van Schothorst, Evert M.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562665/
https://ncbi.nlm.nih.gov/pubmed/31083422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10050359
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