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A Premature Stop Codon in RAF1 Is the Priority Candidate Causative Mutation of the Inherited Chicken Wingless-2 Developmental Syndrome

The chicken wingless-2 (wg-2) mutation is inherited in an autosomal recessive fashion, and the resulting phenotype in mutant (wg-2/wg-2) individuals is a developmental syndrome characterized by absent wings, truncated legs, craniofacial as well as skin and feather defects, and kidney malformations....

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Pubblicato in:Genes (Basel)
Autori principali: Youngworth, Ingrid, Delany, Mary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562611/
https://ncbi.nlm.nih.gov/pubmed/31075853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10050353
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