Zebrafish Carrying pycr1 Gene Deficiency Display Aging and Multiple Behavioral Abnormalities

Aging is a natural process that internal gene control and external stimuli mediate. Clinical data pointed out that homozygotic or heterozygotic mutation in the pyrroline-5-carboxylate reductase 1 (PYCR1) gene in humans caused cutis laxa (ARCL) disease, with progeroid appearance, lax and wrinkled ski...

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Bibliographic Details
Published in:Cells
Main Authors: Liang, Sung-Tzu, Audira, Gilbert, Juniardi, Stevhen, Chen, Jung-Ren, Lai, Yu-Heng, Du, Zheng-Cai, Lin, Dar-Shong, Hsiao, Chung-Der
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562453/
https://ncbi.nlm.nih.gov/pubmed/31091804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8050453
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