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NF-κB in the crosshairs: Rethinking an old riddle
Constitutive NF-κB signalling has been implicated in the pathogenesis of most human malignancies and virtually all non-malignant pathologies. Accordingly, the NF-κB pathway has been aggressively pursued as an attractive therapeutic target for drug discovery. However, the severe on-target toxicities...
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| Publicado no: | Int J Biochem Cell Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6562234/ https://ncbi.nlm.nih.gov/pubmed/29277662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2017.12.020 |
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