NKX2-8 deletion-induced reprogramming of fatty acid metabolism confers chemoresistance in epithelial ovarian cancer

BACKGROUND: Aberrant fatty acid (FA) metabolism is a unique vulnerability of cancer cells and may present a promising target for cancer therapy. Our study aims to elucidate the molecular mechanisms by which NKX2–8 deletion reprogrammed FA metabolism-induced chemoresistance in epithelial ovarian canc...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Zhu, Jinrong, Wu, Geyan, Song, Libing, Cao, Lixue, Tan, Zhanyao, Tang, Miaoling, Li, Ziwen, Shi, Dongni, Zhang, Shuxia, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562195/
https://ncbi.nlm.nih.gov/pubmed/31047858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.041
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