Blood neurofilament light as a potential endpoint in Phase 2 studies in MS

OBJECTIVES: To assess whether neurofilament light chain (NfL) could serve as an informative endpoint in Phase 2 studies in patients with relapsing–remitting multiple sclerosis (RRMS) and estimate the sample size requirements with NfL as the primary endpoint. METHODS: Using data from the Phase 3 FREE...

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Detalles Bibliográficos
Publicado en:Ann Clin Transl Neurol
Main Authors: Sormani, Maria Pia, Haering, Dieter A., Kropshofer, Harald, Leppert, David, Kundu, Uma, Barro, Christian, Kappos, Ludwig, Tomic, Davorka, Kuhle, Jens
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562031/
https://ncbi.nlm.nih.gov/pubmed/31211172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.795
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