Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland

Polygenic scores (PSs) are becoming a useful tool to identify individuals with high genetic risk for complex diseases, and several projects are currently testing their utility for translational applications. It is also tempting to use PSs to assess whether genetic variation can explain a part of the...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Kerminen, Sini, Martin, Alicia R., Koskela, Jukka, Ruotsalainen, Sanni E., Havulinna, Aki S., Surakka, Ida, Palotie, Aarno, Perola, Markus, Salomaa, Veikko, Daly, Mark J., Ripatti, Samuli, Pirinen, Matti
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562021/
https://ncbi.nlm.nih.gov/pubmed/31155286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.05.001
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