Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechanism in advanced gastric cancer

BACKGROUND: Circulating tumor DNA (ctDNA) isolated from plasma contains genetic mutations that can be representative of those found in primary tumor tissue DNA. These samples can provide insights into tumoral heterogeneity in patients with advanced gastric cancer (AGC). Although trastuzumab has been...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Wang, Yan, Zhao, Chuanhua, Chang, Lianpeng, Jia, Ru, Liu, Rongrui, Zhang, Yun, Gao, Xuan, Li, Jin, Chen, Rongrong, Xia, Xuefeng, Bulbul, Ajaz, Husain, Hatim, Guan, Yanfang, Yi, Xin, Xu, Jianming
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2019
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562020/
https://ncbi.nlm.nih.gov/pubmed/31031019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.003
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