Circulating tumor DNA analyses predict progressive disease and indicate trastuzumab-resistant mechanism in advanced gastric cancer

BACKGROUND: Circulating tumor DNA (ctDNA) isolated from plasma contains genetic mutations that can be representative of those found in primary tumor tissue DNA. These samples can provide insights into tumoral heterogeneity in patients with advanced gastric cancer (AGC). Although trastuzumab has been...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wang, Yan, Zhao, Chuanhua, Chang, Lianpeng, Jia, Ru, Liu, Rongrui, Zhang, Yun, Gao, Xuan, Li, Jin, Chen, Rongrong, Xia, Xuefeng, Bulbul, Ajaz, Husain, Hatim, Guan, Yanfang, Yi, Xin, Xu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6562020/
https://ncbi.nlm.nih.gov/pubmed/31031019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.04.003
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