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Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model

Preeclampsia is a human placental disorder affecting 2–8% of pregnancies worldwide annually, with hypertension and proteinuria appearing after 20 weeks of gestation. The underlying cause is believed to be incomplete trophoblast invasion of the maternal spiral arteries during placentation in the firs...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Erlandsson, Lena, Ducat, Aurélien, Castille, Johann, Zia, Isac, Kalapotharakos, Grigorios, Hedström, Erik, Vilotte, Jean-Luc, Vaiman, Daniel, Hansson, Stefan R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561956/
https://ncbi.nlm.nih.gov/pubmed/31189914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44639-9
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