DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

Mitochondrial quality control is essential in highly structured cells such as neurons and muscles. In skeletal muscle the mitochondrial fission proteins are reduced in different physiopathological conditions including ageing sarcopenia, cancer cachexia and chemotherapy-induced muscle wasting. Howeve...

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Published in:Nat Commun
Main Authors: Favaro, Giulia, Romanello, Vanina, Varanita, Tatiana, Andrea Desbats, Maria, Morbidoni, Valeria, Tezze, Caterina, Albiero, Mattia, Canato, Marta, Gherardi, Gaia, De Stefani, Diego, Mammucari, Cristina, Blaauw, Bert, Boncompagni, Simona, Protasi, Feliciano, Reggiani, Carlo, Scorrano, Luca, Salviati, Leonardo, Sandri, Marco
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561930/
https://ncbi.nlm.nih.gov/pubmed/31189900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10226-9
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