The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation

BACKGROUND: Vein-graft bypass is commonly performed to overcome atherosclerosis but is limited by high failure rates, principally due to neointimal wall thickening. Recent studies reveal that endothelial-mesenchymal transition (EndoMT) is critical for vein-graft neointima formation. BETs are a famil...

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Udgivet i:Cell Signal
Main Authors: Zhang, Mengxue, Wang, Bowen, Urabe, Go, Huang, Yitao, Plutzky, Jorge, Kent, K. Craig, Guo, Lian-Wang
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561802/
https://ncbi.nlm.nih.gov/pubmed/31075399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.05.005
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