Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface

Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo signals is a promising new approach for the diagnosis, treatment, and prevention of disease. However, because the design of disease-responsive circuits is limited by a relatively small pool of known bios...

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Bibliografische gegevens
Gepubliceerd in:mSystems
Hoofdauteurs: Naydich, Alexander D., Nangle, Shannon N., Bues, Johannes J., Trivedi, Disha, Nissar, Nabeel, Inniss, Mara C., Niederhuber, Matthew J., Way, Jeffrey C., Silver, Pamela A., Riglar, David T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561318/
https://ncbi.nlm.nih.gov/pubmed/31186335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00125-19
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