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Positron emission tomography reporter gene strategy for use in the central nervous system

There is a growing need for monitoring or imaging gene therapy in the central nervous system (CNS). This can be achieved with a positron emission tomography (PET) reporter gene strategy. Here we report the development of a PET reporter gene system using the PKM2 gene with its associated radiotracer...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Haywood, Tom, Beinat, Corinne, Gowrishankar, Gayatri, Patel, Chirag B., Alam, Israt S., Murty, Surya, Gambhir, Sanjiv Sam
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561252/
https://ncbi.nlm.nih.gov/pubmed/31123153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901645116
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