Destabilization of the human RED–SMU1 splicing complex as a basis for host-directed antiinfluenza strategy

New therapeutic strategies targeting influenza are actively sought due to limitations in current drugs available. Host-directed therapy is an emerging concept to target host functions involved in pathogen life cycles and/or pathogenesis, rather than pathogen components themselves. From this perspect...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ashraf, Usama, Tengo, Laura, Le Corre, Laurent, Fournier, Guillaume, Busca, Patricia, McCarthy, Andrew A., Rameix-Welti, Marie-Anne, Gravier-Pelletier, Christine, Ruigrok, Rob W. H., Jacob, Yves, Vidalain, Pierre-Olivier, Pietrancosta, Nicolas, Crépin, Thibaut, Naffakh, Nadia
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561211/
https://ncbi.nlm.nih.gov/pubmed/31076555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901214116
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