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Caulobacter crescentus Hfq structure reveals a conserved mechanism of RNA annealing regulation

We have solved the X-ray crystal structure of the RNA chaperone protein Hfq from the alpha-proteobacterium Caulobacter crescentus to 2.15-Å resolution, resolving the conserved core of the protein and the entire C-terminal domain (CTD). The structure reveals that the CTD of neighboring hexamers pack...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Santiago-Frangos, Andrew, Fröhlich, Kathrin S., Jeliazkov, Jeliazko R., Małecka, Ewelina M., Marino, Giada, Gray, Jeffrey J., Luisi, Ben F., Woodson, Sarah A., Hardwick, Steven W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6561178/
https://ncbi.nlm.nih.gov/pubmed/31076551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814428116
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