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COMT polymorphism regulates the hippocampal subfield volumes in first-episode, drug-naive patients with major depressive disorder

Purpose: Compared with healthy subjects (HS), patients with major depressive disorder (MDD) exhibit volume differences that affect the volume changes in several areas such as the limbic, cortical, subcortical, and white matter. Catechol-O-methyltransferase (COMT) is a methylation enzyme that catalyz...

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Bibliografske podrobnosti
izdano v:Neuropsychiatr Dis Treat
Main Authors: Otsuka, Yuka, Kakeda, Shingo, Sugimoto, Koichiro, Katsuki, Asuka, Nguyen, Le Hoa, Igata, Ryohei, Watanabe, Keita, Ueda, Issei, Kishi, Taro, Iwata, Nakao, Korogi, Yukunori, Yoshimura, Reiji
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560253/
https://ncbi.nlm.nih.gov/pubmed/31239688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S199598
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