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Indoleamine 2,3-dioxygenase and ischemic heart disease: a Mendelian Randomization study

Tryptophan is an essential amino acid. Indoleamine 2,3-dioxygenase (IDO), the rate-limiting enzyme in the tryptophan-kynurenine pathway, is positively associated with cardiac events, and may be relevant to cancer. We used Mendelian Randomization to obtain unconfounded estimates of the association of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Mengyu, Kwok, Man Ki, Fong, Shirley Siu Ming, Schooling, Catherine Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560130/
https://ncbi.nlm.nih.gov/pubmed/31186442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44819-7
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