Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation

Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects. However, the underlying mechanisms remain elusive. Whether GLP regulates autophagy in cancer has never been reported. In this study,...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Pan, Haitao, Wang, Yujie, Na, Kun, Wang, Ying, Wang, Lu, Li, Zhenhao, Guo, Chengjie, Guo, Dandan, Wang, Xingya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560101/
https://ncbi.nlm.nih.gov/pubmed/31186406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1653-7
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