Toll-like Receptor-4 Activation Boosts the Immunosuppressive Properties of Tumor Cells-derived Exosomes

The biology of tumor-derived exosomes (TEX) is only partially understood and much remains to be studied in order to define the effect that the tumor microenvironment or the activation of tumor cells exerts on their composition and functions. Increased expression and activity of toll-like receptor 4...

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Udgivet i:Sci Rep
Main Authors: Domenis, Rossana, Cifù, Adriana, Marinò, Daniele, Fabris, Martina, Niazi, Kayvan R., Soon-Shiong, Patrick, Curcio, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6560033/
https://ncbi.nlm.nih.gov/pubmed/31186484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44949-y
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